abstract：:A polysaccharide-rich fraction (ATF) of medicinal mushroom Agaricus brasiliensis was evaluated on the candidacidal activity, H2O2 and nitric oxide (NO) production, and expression of mannose receptors by murine peritoneal macrophages. Mice received three intraperitoneal (i.p.) injections of ATF and after 48 h their per...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martins PR,Gameiro MC,Castoldi L,Romagnoli GG,Lopes FC,Pinto AV,Loyola W,Kaneno R

更新日期：2008-05-01 00:00:00

abstract：:Several studies conducted all over the world have reported that the influenza virus is associated with great morbidity and mortality rates. In this study, we analyzed the incidence of the influenza virus between 2000 and 2003 in Curitiba. We studied 1621 samples obtained from outpatients and hospitalized patients of b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vidal LR,Siqueira MM,Nogueira MB,Raboni SM,Pereira LA,Takahashi GR,Rotta I,Debur Mdo C,Dalla-Costa LM

更新日期：2008-03-01 00:00:00

abstract：:The purpose of this study was to investigate the genotypes of Giardia lamblia from human and animal feces and their epidemiological and clinical characteristics in Argentina, South America. Seventy isolates, 60 from humans (adults and children), eight from dogs and two from cows were processed by polymerase chain reac...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Minvielle MC,Molina NB,Polverino D,Basualdo JA

更新日期：2008-02-01 00:00:00

abstract：:Infection of C3H/He mice with the Peruvian strain of Trypanosoma cruzi (Biodeme type I, Z2b), a macrophagotropic strain, determined severe parasitism of macrophages, necrosis of the spleen, and high host mortality. In the present study, pentoxifylline (PTX), an inhibitor of TNF-alpha was investigated on its action upo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Andrade SG,Magalhães Ldos A,Pessina DH

更新日期：2008-02-01 00:00:00

abstract：:In Argentina, most information on hepatitis C virus (HCV) genotype distribution comes from studies carried out in Buenos Aires (east province). In order to identify HCV subtypes in central Argentina, nucleotide sequencing of core region was performed in samples from 36 patients living in Córdoba, the second most popul...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ré V,Contigiani M,Yoshida CF,Lampe E

更新日期：2007-12-01 00:00:00

abstract：:Aspects related to hatching, lifetime, number of blood meals for molting, mortality, feeding time, and postfeeding defecation delay were evaluated and compared in each instar of three North American Triatominae: Triatoma gerstaeckeri, Triatoma lecticularia and Triatoma protracta, all of them fed on rabbits. No signifi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martínez-Ibarra JA,Alejandre-Aguilar R,Paredes-González E,Martínez-Silva MA,Solorio-Cibrián M,Nogueda-Torres B,Trujillo-Contreras F,Novelo-López M

更新日期：2007-12-01 00:00:00

abstract：:In this article, Médicos Sin Fronteras (MSF) Spain faces the challenge of selecting, piecing together, and conveying in the clearest possible way, the main lessons learnt over the course of the last seven years in the world of medical care for Chagas disease. More than two thousand children under the age of 14 have be...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Villa L,Morote S,Bernal O,Bulla D,Albajar-Vinas P

更新日期：2007-10-30 00:00:00

abstract：:Neisseria meningitidis retains its ability to cause endemic and hiperendemic disease in human population living in any environment, as well as localized outbreaks and massive epidemics in civilians and military personnel. In Rio de Janeiro it has been reported in the 1990s as prolonged outbreak of serogroup B and at l...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barroso DE,Rebelo MC

更新日期：2007-09-01 00:00:00

abstract：:The aim of this study was to test if serological distinction between patients with active and inactive neurocysticercosis (NCC), could be accomplished by the recognition of immunodominant peptides in total saline antigenic extract of Taenia solium metacestodes by IgG antibody in cerebrospinal fluid (CSF) and serum pai...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barcelos IS,Moura LP,Costa VP,Ferreira MS,Costa-Cruz JM

更新日期：2007-09-01 00:00:00

abstract：:Early Cretaceous flagellates with characters typical of trypanosomatids were found in the gut of sand fly larvae, as well as in surrounding debris, in Burmese amber. This discovery supports a hypothesis in which free-living trypanosomatids could have been acquired by sand fly larvae in their feeding environment and th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Poinar G Jr

更新日期：2007-08-01 00:00:00

abstract：:The great difficulties in treating people and animals suffering from cryptosporidiosis have prompted the development of in vitro experimental models. Due to the models of in vitro culture, new extracellular stages of Cryptosporidium have been demonstrated. The development of these extracellular phases depends on the t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Perez Cordón G,Marin C,Romero D,Rosales C,Sánchez Moreno M,Rosales MJ

更新日期：2007-08-01 00:00:00

abstract：:The antibody response to Plasmodium falciparum parasites of naturally infected population is critical to elucidate the role of polymorphic alleles in malaria. Thus, we evaluated the impact of antigenic diversity of repetitive and family dimorphic domains of the merozoite surface protein 2 (MSP-2) on immune response of...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sallenave-Sales S,Faria CP,Zalis MG,Daniel-Ribeiro CT,Ferreira-da-Cruz Mde F

更新日期：2007-06-01 00:00:00

abstract：:We analyzed prospectively 326 laboratory-confirmed, uncomplicated malarial infections (46.3% due to Plasmodium vivax, 35.3% due to P. falciparum, and 18.4% mixed-species infections) diagnosed in 162 rural Amazonians aged 5-73 years. Thirteen symptoms (fever, chills, sweating, headache, myalgia, arthralgia, abdominal p...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： da Silva-Nunes M,Ferreira MU

更新日期：2007-06-01 00:00:00

abstract：:Cross sectional studies on malaria prevalence was performed in 2001, 2002, and 2004 in Vila Candelária, an urban riverside area of Porto Velho, Rondônia, in the Brazilian Western Amazon, followed by longitudinal surveys on malaria incidence. Vila Candelária is a working class district, provided with electricity, water...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Tada MS,Marques RP,Mesquita E,Dalla Martha RC,Rodrigues JA,Costa JD,Pepelascov RR,Katsuragawa TH,Pereira-da-Silva LH

更新日期：2007-06-01 00:00:00

abstract：:Seasonal variation in container productivity and infestation levels by Aedes aegypti were evaluated in two areas with distinct levels of urbanization degrees in Rio de Janeiro, a slum and a suburban neighborhood. The four most productive containers can generate up to 90% of total pupae. Large and open-mouthed containe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Maciel-de-Freitas R,Marques WA,Peres RC,Cunha SP,de Oliveira RL

更新日期：2007-06-01 00:00:00

abstract：:Patients with acute schistosomiasis were studied before and after oxamniquine treatment. They had been exposed to cercariae 5 to 9 weeks before, and presented compatible clinical manifestations, eosinophilia, and high levels of total IgE. Interferon-gamma (IFN-gamma) and interleukin-4 were measured by ELISA in whole b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Souza JR,Morais CN,Aroucha ML,Miranda PJ,Barbosa CS,Domingues AL,Carvalho Júnior LB,Abath FG,Montenegro SM

更新日期：2007-05-01 00:00:00

abstract：:Lutzomyia (Lutzomyia) falquetoi, sp. nov. (Diptera: Psychodidae, Phlebotominae) is described from the state of Espírito Santo, Brazil. This new species belongs to the series longipalpis and is easily distinguished from the other members of this taxon by the presence of five well-developed spines and a pre-apical spini...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pinto Ide S,Dos Santos CB

更新日期：2007-05-01 00:00:00

abstract：:The mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Zacks MA

更新日期：2007-02-01 00:00:00

abstract：:Resistance in Mycobacterium tuberculosis to isoniazid (INH) is caused by mutations in the catalase-peroxidase gene (katG), and within the inhA promoter and/or in structural gene. A small percentage (approximately 10%) of INH-resistant strains do not present mutations in both of these loci. Other genes have been associ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardoso RF,Cardoso MA,Leite CQ,Sato DN,Mamizuka EM,Hirata RD,de Mello FF,Hirata MH

更新日期：2007-02-01 00:00:00

abstract：:The sample consists of 226 skulls from the Atacameño cemetery of Coyo Oriente (639-910 AD), associated with the Tiwanaku period. The authors analyzed signs of acute trauma typically associated with violence, and the results were 12% of men and 9.9% of women displaying any type of lesion related to violence. In males, ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Lessa A,de Souza SM

更新日期：2006-12-05 00:00:00

abstract：:Phlebotominae includes some vector species, mainly that of leishmaniases, with a very old host-parasite relationship. Some species fossils of this subfamily have been recently described and this paper presents the description of a new sand fly Pintomyia (Pifanomyia) paleotownsendi sp. nov in amber. The gonostyle prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Filho JD,Falcão AL,Galati EA,Brazil RP

更新日期：2006-12-05 00:00:00

abstract：:Dengue outbreaks have occurred in several regions in Brazil and cocirculating dengue virus type 1 (DENV-1), DENV-2, and DENV-3 have been frequently observed. Dual infection by DENV-2 and DENV-3 was identified by type-specific indirect immunofluorescence assay and confirmed by reverse transcription polymerase chain rea...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Araújo FM,Nogueira RM,de Araújo JM,Ramalho IL,Roriz ML,de Melo ME,Coelho IC

更新日期：2006-12-01 00:00:00

abstract：:In schistosomiasis, the host/parasite interaction remains not completely understood. Many questions related to the susceptibility of snails to infection by respective trematode still remain unanswered. The control of schistosomiasis requires a good understanding of the host/parasite association. In this work, the susc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abdel-Hamid AH,Rawi SM,Arafa AF

更新日期：2006-12-01 00:00:00

abstract：:The lymneid snail Lymnaea bogotensis Pilsbry 1935 is synonymized with L. cousini Jousseaume 1887, based on morphological comparisons of the reproductive systems. The shell, renal tube, and reproductive system are described and illustrated from specimens collected in the type locality and the municipality of Paipa, Col...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Velásquez LE

更新日期：2006-11-01 00:00:00

abstract：:In Mexico, despite the relatively high seroprevalence of Trypanosoma cruzi infection in humans in some areas, reported morbidity of Chagas disease is not clear. We determined clinical stage in 71 individuals seropositive to T. cruzi in the state of Puebla, Mexico, an area endemic for Chagas disease with a reported ser...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sánchez-Guillén Mdel C,López-Colombo A,Ordóñez-Toquero G,Gomez-Albino I,Ramos-Jimenez J,Torres-Rasgado E,Salgado-Rosas H,Romero-Díaz M,Pulido-Pérez P,Pérez-Fuentes R

更新日期：2006-11-01 00:00:00

abstract：:The high level of protection elicited in rodents and primates by the radiation-attenuated schistosome vaccine gives hope that a human vaccine relying on equivalent mechanisms is feasible. In humans, a vaccine would be undoubtedly administered to previously or currently infected individuals. We have therefore used the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Coulson PS,Kariuki TM

更新日期：2006-09-01 00:00:00

abstract：:In a previous study, the Schistosoma mansoni Rho1 protein was able to complement Rho1 null mutant Saccharomyces cerevisiae cells at restrictive temperatures and under osmotic stress (low calcium concentration) better than the human homologue (RhoA). It is known that under osmotic stress, the S. cerevisiae Rho1 trigger...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Aguiar PH,Santos DN,Lobo FP,Santos TM,Macedo AM,Pena SD,Machado CR,Franco GR

更新日期：2006-09-01 00:00:00

abstract：:Hepatosplenic schistosomiasis was the first human disease in which the possibility of extensive long standing hepatic fibrosis being degraded and removed has been demonstrated. When such changes occurred, the main signs of portal hypertension (splenomegaly, esophageal varices) progressively disappeared, implying that ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Andrade ZA,Baptista AP,Santana TS

更新日期：2006-09-01 00:00:00

abstract：:Biomphalaria glabrata can react through different pathways to Schistosoma mansoni miracidium penetration, according to the degree of resistance/susceptibility presented by different snail strains, which is a genetically determined character, resistance being the dominant feature. However, it has been observed that pre...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Azevedo CM,Borges CC,Andrade ZA

更新日期：2006-09-01 00:00:00

abstract：:This report describes the development of a SYBR Green I based real time polymerase chain reaction (PCR) protocol for detection on the ABI Prism 7000 instrument. Primers targeting the gene encoding the SSU rRNA were designed to amplify with high specificity DNA from Schistosoma mansoni, in a real time quantitative PCR ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gomes AL,Melo FL,Werkhauser RP,Abath FG

更新日期：2006-09-01 00:00:00

abstract：:The Program for Schistosomiasis Control within the Unified Health System (PCE-SUS) was implemented by 1999 in the Rainforest Zone or "Zona da Mata" of Pernambuco (ZMP) aiming to carry out biennial stool surveys of whole populations through municipal health organs followed by treatment of the positives through the loca...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Favre TC,Ximenes RA,Galvão AF,Pereira AP,Wanderlei TN,Barbosa CS,Pieri OS

更新日期：2006-09-01 00:00:00

abstract：:Coagulase-negative staphylococci (CNS) have been identified as the etiological agent in various infections and are currently the microorganisms most frequently isolated in nosocomial infections. However, little is known about the virulence factors produced by CNS that contribute to the pathogenesis of infections cause...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cunha Mde L,Rugolo LM,Lopes CA

更新日期：2006-09-01 00:00:00

abstract：:Mutations in the rpoB locus confer conformational changes leading to defective binding of rifampin (RIF) to rpoB and consequently resistance in Mycobacterium tuberculosis. Polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) was established as a rapid screening test for the detection of mutatio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Isfahani BN,Tavakoli A,Salehi M,Tazhibi M

更新日期：2006-09-01 00:00:00

abstract：:The susceptibility of Anopheles aquasalis (F3 generation) and An. darlingi (F1 generation) to Plasmodium vivax circumsporozoite protein phenotypes from a limited number of blood samples of malaria patients in Belém, state of Pará, Brazil, was examined A polymerase chain reaction was used to determine the P. vivax phen...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： da Silva AN,Santos CC,Lacerda RN,Machado RL,Póvoa MM

更新日期：2006-08-01 00:00:00

abstract：:Trypanosoma cruzi acute infections often go unperceived, but one third of chronically infected individuals die of Chagas disease, showing diverse manifestations affecting the heart, intestines, and nervous systems. A common denominator of pathology in Chagas disease is the minimal rejection unit, whereby parasite-free...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teixeira AR,Nascimento RJ,Sturm NR

更新日期：2006-08-01 00:00:00

abstract：:In Brazil, until 2004, the immunization policy against diphtheria involved childhood vaccination with no official routine booster dose administered after 15 years of age. This study assessed functional antibody levels against diphtheria among blood donors. A total of 140 blood samples were collected, and diphtheria an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pimenta FP,Damasco PV,Cerbino Neto J,Lopes GS,Hirata R Jr,Milagres LG,Mattos-Guaraldi AL

更新日期：2006-06-01 00:00:00

abstract：:The objective of this study was to evaluate the relationship between toxocariasis frequency and demographic, environmental, sanitary variables, eosinophylia, and other intestinal parasites in a rural population of Argentina. Serological examination of 100 individuals was carried out by using ELISA technique for the de...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Chiodo P,Basualdo J,Ciarmela L,Pezzani B,Apezteguía M,Minvielle M

更新日期：2006-06-01 00:00:00

abstract：:In recent years, the development of new tools to gather field information about vector ecological parameters has increased. This report evaluated the BG-Sentinel Trap (BGS-Trap), a promising new attempt to improve collection of the dengue vector, Aedes aegypti. The efficacy of the BGS-Trap was compared with the CDC ba...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Maciel-de-Freitas R,Eiras AE,Lourenço-de-Oliveira R

更新日期：2006-05-01 00:00:00

abstract：:Lymphatic filariasis caused by nematode parasites Wuchereria bancrofti or Brugia malayi is a spectral disease and produces wide range of immune responses and varying levels of microfilaraemia in infected individuals. The relationship between the immune response of host and the developmental stage of the parasite as we...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Athisaya Mary K,Hoti S,Paily K

更新日期：2006-05-01 00:00:00

abstract：:The natural lignans veraguensin and grandisin have been reported to be active against Trypanosoma cruzi bloodstream forms. Aiming at the total synthesis of these and related compounds, we prepared three 2-arylfurans and eight 2,5-diarylfurans. They were evaluated for their potential as T. cruzi trypanothione reductase...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Oliveira RB,Vaz AB,Alves RO,Liarte DB,Donnici CL,Romanha AJ,Zani CL

更新日期：2006-03-01 00:00:00